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The American Academy of Pediatrics FALSELY states that “Vaccines are not associated with autism.”

Following is a list of abstracts from 244 papers demonstrating the multiple associations between vaccines and autism.

Autism is a largely immune mediated condition, and the purpose of a vaccine is to change the behavior of the immune system. Vaccines and their ingredients can cause the underlying medical conditions that are commonly found in children who have been given an autism diagnosis. These conditions include immune system impairment, autoimmune conditions, neuroinflammation, gastrointestinal damage, neurological regression, mitochondrial dysfunction, oxidative stress, glial cell activation, interleukin-6 secretion dysregulation, damage to the blood–brain barrier, seizures, dendritic cell dysfunction, mercury poisoning, aluminum toxicity, gene activation and alteration, glutathione depletion, impaired methylation, impaired thioredoxin regulation, impairment of the opioid system, cellular apoptosis, endocrine dysfunction, and other disorders.

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  • April 6, 2023
Aluminum / Toxicants

Aluminium adjuvants and childhood health: a call for science

Abstract
In July 2025, Andersson et al. reported in Annals of Internal Medicine that early-life exposure to Aluminium (Al)-adjuvanted vaccines was not associated with increased risk of 50 chronic diseases, based on a Danish cohort of 1.2 million children. While widely cited as reassuring evidence of Al-Based Adjuvant (ABA) safety, closer scrutiny reveals major methodological and conceptual flaws. Specifically, the study demonstrates limited understanding of Al toxicology, weaknesses in cohort design and statistical analysis, and insufficient transparency regarding potential conflicts of interest. We argue that these shortcomings prevent meaningful conclusions about ABA safety, particularly in relation to neurodevelopmental and autoimmune outcomes, and highlight the need for more rigorous, transparent, and scientifically grounded investigations.

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  • February 10, 2026
Aluminum / Blood brain barrier / Bradford Hill criteria / Epidemiology / HLA / IL-1β / Lymphocytes / MTHFR / Neuroinflammation / NLRP3 / Toxicants

Aluminum Adjuvants, Autoimmunity, and Autism Spectrum Disorder: AComprehensive Mechanistic, Neuropathological, and Legal Analysis

Conclusions: Converging mechanistic, neuropathological, epidemiological, and genetic
evidence demonstrates that aluminum adjuvants can trigger ASD in genetically susceptible
individuals through well-characterized neuroinflammatory pathways. The 80-fold increase
in ASD prevalence temporally correlating with vaccine schedule expansion, combined with
robust biological mechanisms and postmortem findings, demands urgent re-examination of aluminum adjuvant safety in the context of neurodevelopment, particularly in genetically vulnerable populations.

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  • February 2, 2026
Autoimmunity / GI / Immune / Neuroinflammation / Review

The Neuroimmunology of Autism

Excerpt:

“intensifying evidence confirms that much of what ASD involves is related not to a static encephalopathy-based model of autism but rather to the consequences of environmental insult and complex and dynamic psychological and physiological processes involving the interdependence of the nervous, immune, and host microbiome.”

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  • December 20, 2025
Encephalopathy / infection

Vaccine-Induced Viral Reactivation and Autism Spectrum Disorder: A Review, Hypothesis, and Implications

Excerpt:
This search yielded 13 studies implicating viral infections and viral encephalitis as potential causal factors in the development of autism spectrum disorder. Moreover, 17 studies were identified, suggesting an association of viral reactivation following vaccination. This connection raises important questions about the role of vaccines in the onset of autism.

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  • December 11, 2025
Adjuvant / Aluminum / Autoimmunity / Genes / GI / Immune / Mercury / Mitochondria / MMR / Neurons / Pregnancy / Thimerosal

McCullough Foundation Report: Determinants of Autism Spectrum Disorder

Conclusion: The totality of evidence supports a multifactorial model of ASD in which genetic predisposition, neuroimmune biology, environmental toxicants, perinatal stressors, and iatrogenic exposures converge to produce the phenotype of a post-encephalitic state. Combination and early-timed routine childhood vaccination constitutes the most significant modifiable risk factor for ASD, supported by convergent mechanistic, clinical, and epidemiologic findings, and characterized by intensified use, the clustering of multiple doses during critical neurodevelopmental windows, and the lack of research on the cumulative safety of the full pediatric schedule. As ASD prevalence continues to rise at an unprecedented pace, clarifying the risks associated with cumulative vaccine dosing and timing remains an urgent public health priority.

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  • October 27, 2025
intellectual disability / IQ / Pregnancy / Prevalence / severity / Thimerosal

Time Trends in United States Autism Prevalence with Co-Occurring Intellectual Disability: Is There a Signature of Thimerosal?

Excerpt:
“The sharp drop in the ID fraction between birth year 2000 and 2002 coincided with the removal of thimerosal, a mercury-containing preservative and neurotoxin linked to autism severity, from most childhood vaccines. Conversely, the renewed increase in the ID fraction after 2006 coincided with the reintroduction of thimerosal via flu shots promoted for infants and pregnant women. Low-income women and children are particularly likely to receive those products in some states, due to health insurance and daycare requirements, which may be contributing to autism severity as well as to the recent strong divergence in ASD prevalence by race/ethnicity.”

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  • June 25, 2025
Adjuvant / Excitotoxicity / Glial Cells / Glutamate / IL-6 / Immune / Mitochondria / Neuroinflammation / Review / TNF-α

Autism Spectrum Disorders: Is Immunoexcitotoxicity the Link to the Vaccine Adjuvants? The Evidence

Exerpt
“any adjuvant or condition boosting immune activation of certain cells, such as Central Nervous System (CNS) microglia and macrophages, if sequentially activated by the vaccination process, whatever the adjuvant or immune stimulation principle, will trigger this mechanism, not only in the CNS, but possibly other peripheral organs and tissues containing glutamate receptors”

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  • May 1, 2025
BDNF / Glial Cells / Mercury / Neurons / Toxicants

Assessing the health hazards of low-dose ethylmercury: Neurochemical and behavioral impacts in neonatal mice through matrix metalloproteinase activation and brain-derived neurotrophic factor release

Highlights
•Exposure to ethylmercury (EtHG) poses neurotoxic risks in children.
•Behavioral abnormalities were induced by EtHg exposure in neonatal mice.
•Changes in neurite length and BDNF expression were observed.
•EtHg induces physiological changes in the brain by activating microglia.

Excerpt
“Our findings revealed that EtHg exposure led to significant alterations in brain development, including increased brain size and cortical thickness. These structural changes were accompanied by notable impairments in social interactions and behavioral patterns. Further analysis indicated that these effects were likely mediated by increased microglial activation and elevated BDNF expression in the cerebral cortex. Overall, our study suggests that EtHg disrupts neurodevelopment by activating microglia, leading to physiological and morphological changes in the brain.

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  • March 15, 2025
Preterm / Vaccine Schedule

Vaccination and Neurodevelopmental Disorders: A Study of Nine-Year-Old Children Enrolled in Medicaid

Excerpt: “the relative risk of ASD increased according to the number of visits that included vaccinations. ”
“Conclusions: These results suggest that the current vaccination schedule may be contributing to multiple forms of NDD; that vaccination coupled with preterm birth was strongly associated with increased odds of NDDs compared to preterm birth in the absence of vaccination; and increasing numbers of visits that included vaccinations were associated with increased risks of ASD.”

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  • January 23, 2025
Antioxidant / Glutathione / Mercury / Mitochondria / Oxidative Stress / Thimerosal

Does acute exposure to thimerosal, an organic mercury compound, affect the mitochondrial function of an infant model?

Highlights

• Thimerosal (TM) significantly affects mitochondrial bioenergetics in the brain.
• Mitochondrial integrity (membrane potential) was maintained after acute TM treatment.
• Ethylmercury released after the breakdown of TM compromised the cholinergic system.
• The brain is more sensitive to oxidative stress induced by TM compared to the liver.

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  • February 6, 2024

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